Product Name: Povidone;Povidone; povidonum;Polyvinylpyrrolidone (PVP)
CAS NO.:9003-39-8
Specification
TYPE K VALUE MV
K12 10.2 – 13.8 3,000 – 7,000
K15 12.75 – 17.25 8,000 – 12,000
K17 15.3 – 18.36 10,000 – 16,000
K25 22.5 – 27.0 30,000 – 40,000
K30 27 – 32.4 45,000 – 58,000
K60 54 – 64.8 270,000 – 400,000
K90 81 – 97.2 1,000,000 – 1,500,000
Product Properties:
Nontoxic; Non-irritant; Hygroscopic; Freely soluble in water, alcohol and most other organic solvents; Very slightly soluble in acetone; Excellent solubility; Film-forming; Chemical stability; Physiologically inert; Complexation and binding property.
Applications:
Polyvinylpyrrolidone (PVP) possess excellent binding, film-forming, dispersing and thickening properties and are widely used in the following dosage forms:
• Binder: suitable for wet and dry granulation and direct compression in tableting, improves particle compressibility and can be added to powder blends in dry or granulated forms by the addition of water, alcohol or hydro-alcoholic solutions.
• Solubilizer: suitable for oral and parenteral formulations, enhancing the solubility of poorly soluble drugs in solid dispersion forms.
• Coating agent or binder: coating of active pharmaceutical ingredients on a support structure.
• Suspending, stabilizing or viscosity-modifying agent: suitable for topical and oral suspension and solution applications. The solubility of poorly soluble drugs may be enhanced by combining with KoVidone.
Packing: 25kg/drums
Storage: Placed in an airtight container in dry, avoid light environment